Omnacortil falls in the category of drugs called corticosteroids. This medicine contains a powerful active ingredient called Prednisolone. The corticosteroids act to control an intense immune response of the body to a potentially less harmful allergen. This drug works effectively to blocks certain chemicals in the body that activate inflammatory reactions in your body. Omnacortil medicine helps to control inflammation and controls allergic reactions. Take this medicine as directed to decrease the inflammation caused by an allergen.