- Prescription medication comes as a delayed-release capsule, and packets of delayed-release (long-acting) granules for suspension (to be mixed with liquid) to take by mouth. Nonprescription (over-the-counter) Generic prilosec comes as a delayed-release capsule or tablet to take by mouth.
- The delayed-release capsules and the granules should be taken at least 1 hour before a meal.
- They are usually taken once a day before a meal but may be taken twice a day when used with other medications to eliminate H. pylori, or up to three times a day when used to treat conditions in which the stomach produces too much acid.
- The nonprescription delayed-release generic prilosec tablets or capsules are usually taken once a day in the morning at least 1 hour before eating for 14 days in a row. Additional 14-day treatments may be repeated once every 4 months if needed.