The standard dosage of Aspadol is 10mg. Its active ingredient Tapendol acts efficiently to inhibit the naturally occurring brain chemical that causes pain sensation. This process leads to enhanced extracellular norepinephrine (NE). It is the prime mechanism of Aspadol. To inhibit the reuptake of the brain chemical Aspadol binds to MOR receptors, which helps to increase the level of a brain chemical called noradrenaline. This whole process will lead to palliating pain. The Aspadol drug is rapidly absorbed in the blood; therefore, it works instantly.