The precise working of Generic Aralen in preventing and treating malaria is unclear. But, it has been found through studies that chloroquine blocks the entry of pathogens in the red blood cells (RBCs). Malarial parasites target the human red blood cells, invade them, and cause infection. Chloroquine prevents the pathogen from breaking hemoglobin down in RBCs. In simple words, Generic Aralen keeps malaria parasites from entering the blood cells, preventing infection. The drug is effective against certain strains of Plasmodium falciparum, vivax, malariae, and ovale.