The entire process of how Tadalafil works

Tadalafil , a drug used to treat Erectile Dysfunction, works by emphasizing the effectiveness of an already occurring physiological process at work during the development of an erection. Normally, this cyclical guanosine monophosphate is degraded by PDE5, a substance found in various tissues. PDE5 is reduced after taking Tadalafil, and this reduced quantity of the substance causes a corresponding increase in levels of cyclical guanosine monophosphate, and as a result, a strong erection takes place.

An erection must begin with sexual arousal or physical sexual stimulation. This arousal or stimulation causes a cascading release of nitric oxide to the penis, and this nitric oxide binds with penile receptors to create a new enzyme called cyclical guanosine monophosphate. This cyclical guanosine monophosphate works to create an erection by loosening and relaxing the walls of the arteries in the penis. The relaxed artery walls become engorged with blood, and an erection is created.

Sildenafil is effective for about 4 hours, while Tadalafil remains effective for as long as 36 hours after consumption. This is the reason why Tadalafil has also become known as the "weekend pill". Many men report that they appreciate the increased sexual freedom and spontaneity afforded by the longer acting Tadalafil.

An erection cannot begin without the arousal that causes the cascade of nitric oxide to the penis. Without this nitric oxide, there will be no cyclical guanosine monophosphate created, and hence, no erection. For this reason men need not worry about inappropriate erections after taking the medication. Tadalafil only helps along a process that must begin with arousal.

Tadalafil is safe and effective for the vast majority of men. If you suffer from any degree of Erectile Dysfunction, you should discuss your treatment options with your doctor. It is estimated that 40 million men in America alone suffer from some Erectile Dysfunction, so you shouldn't feel embarrassed about initiating the subject with your doctor.